Acute Interstitial Nephritis

Acute interstitial nephritis is a kidney disorder that happens when the kidneys are unable to filter waste and fluid properly due to inflammation of the kidney.

  • Causes

    Acute interstitial nephritis can be caused by:


    • Certain medications

      • Antibiotics
      • Anti-ulcer drugs
      • Nonsteroidal anti-inflammatory drugs
      • Diuretics

    • Infections such as:

      • Streptococcus
      • Herpes
      • Mumps
      • Hepatitis C
      • Syphilis
      • HIV

    • Conditions that affect the immune system such as
      lupus

  • Definition

    Acute interstitial nephritis is a kidney disorder that happens when the kidneys are unable to filter waste and fluid properly due to inflammation of the kidney.

    Anatomy of the Kidney
    Glomerulonephritis
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  • Diagnosis

    Your doctor will ask about your symptoms and medical history. A physical exam will be done. Tests may include:

    • Blood Tests
    • Urine tests

    • Kidney
      biopsy

    • Kidney
      ultrasound

  • Prevention

    To help reduce your chances of developing acute interstitial nephritis, your doctor may suggest you avoid certain medications such as penicillin or nonsteroidal anti-inflammatory drugs.

  • Risk Factors

    Risk factors that increase your chance of developing acute interstitial nephritis include:

    • In adults: drug or medication use
    • In children: infection

  • Symptoms

    Symptoms include:

    • Decrease in urine output
    • Blood in urine
    • Side or loin pain
    • Swelling of the body
    • Nausea and vomiting
    • Loss of appetite
    • Weakness
    • Aching joints
    • Fever
    • Rash

  • Treatment

    Talk with your doctor about the best treatment plan for you. You treatment will depend on the cause of your acute interstitial nephritis. Treatment options include the following: