Leukoplakia

Leukoplakia is a disorder of the mouth’s mucus membranes. White patches form on the tongue or inside of the mouth over weeks or months. This can also occur on the vulva in females, but for unknown reasons. One type, known as hairy leukoplakia, is a type found primarily in people who have HIV or other types of severe immune deficiency.

  • Causes

    Hairy leukoplakia results from infection with the Epstein-Barr virus.

    Leukoplakia usually results from irritants, such as:


    • Pipe or
      cigarette smoking
    • Chewing tobacco or snuff
    • Rough teeth
    • Rough places on dentures, fillings, or crowns

  • Definition


    Leukoplakia is a disorder of the mouth’s mucus membranes. White patches form on the tongue or inside of the mouth over weeks or months. This can also occur on the vulva in females, but for unknown reasons. One type, known as hairy leukoplakia, is a type found primarily in people who have
    HIV
    or other types of severe immune deficiency.

  • Diagnosis

    In most cases, a dentist can diagnose leukoplakia with a mouth exam. To confirm a diagnosis or to check for cancer, an oral brush biopsy may be needed. This involves removing some cells with a small brush. It takes only minutes and is painless. A pathologist then checks these cells for signs of cancer. Sometimes the dentist or oral surgeon uses a scalpel to remove cells after numbing the area.

  • Prevention

    To help reduce your chance of getting leukoplakia, take the following steps:


    • If you smoke,
      quit
      .
    • Avoid or limit your use of alcohol.
    • See a dentist regularly, especially if you have rough places in your mouth.

  • Risk Factors

    Leukoplakia is more common in men after 65 years of age. These other risk factors increase your chance of developing leukoplakia. Tell your doctor if you have any of these risk factors:

    • Sex:
      In women, the condition often develops into
      cancer.

    • Lifestyle:

      • Tobacco use, especially smokeless tobacco

      • Long-time
        alcohol
        use
    • Having a weakened immune system such as from HIV

  • Symptoms

    Symptoms may include:


    • Lesion on the tongue or gums, inside of the cheeks, or on the vulva
      that is:

      • White, gray, or red in color
      • Thick, slightly raised, or hardened on the surface
    • Sensitivity to touch, heat, or spicy foods
    • Pain or other signs of infection
    • With hairy leukoplakia: painless and fuzzy, white appearance


    In some cases, leukoplakia looks like
    oral thrush
    , which is an infection also associated with HIV/AIDS and lowered immune function.

    Oral Thrush—Resembles Leukoplakia
    Thrush
    Copyright © Nucleus Medical Media, Inc.

  • Treatment

    Talk with your doctor about the best treatment plan for you. Treatment options include:

    • Removing the irritant—Quitting smoking or correcting dental problems often takes care of the problem.
    • Removing patches—If the problem persists, or if signs of cancer are present, your dentist or doctor may need to remove patches of leukoplakia.
    • Taking medication—For hairy leukoplakia, the doctor may prescribe antiviral medicines. Or, a solution to apply to the skin may be prescribed.