Immunoglobulin Therapy

Immunoglobulins are special proteins in the blood that fight infections. Some of our white blood cells make them. They are also known as antibodies. Antibodies are important for the immune system. In immunoglobulin therapy (IVIg), extra immunoglobulins from a donor are injected into your blood.

  • Call Your Doctor


    As with the introduction of any foreign substance or chemical to the body, the possibility of allergic reaction exists. If you experience any of the following symptoms of anaphylactic shock (severe allergic reaction), you should call the doctor immediately:


    • Wheezing and/or difficulty breathing
    • Confusion
    • Slurred or abnormal speech
    • Rapid heartbeat or heart palpitations, weak or rapid pulse
    • Blue tint to the skin, lips, or fingernails
    • Dizziness, lightheadedness, or feeling faint
    • Hives, rash, or itching
    • Anxiety

    • Nausea, vomiting,
      diarrhea, or abdominal cramping
    • Cough or nasal congestion
    • Reddened skin

    In case of an emergency, call for medical help right away.

  • Definition

    Immunoglobulins are special proteins in the blood that fight infections. Some of our white blood cells make them. They are also known as antibodies. Antibodies are important for the immune system. In immunoglobulin therapy (IVIg), extra immunoglobulins from a donor are injected into your blood.

    Immune System
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  • What to Expect

    You may begin to see an improvement in your original symptoms as soon as 24-48 hours following the procedure. For some, it may be 3-4 weeks before an improvement is seen.

    Immunoglobulin therapy is usually done in cycles. For an infection or other immune system deficiency, therapy is usually recommended every 3-4 weeks. If you have a neurological or autoimmune disease, therapy is administered for five days a month for 3-6 months. Following the initial therapy, maintenance therapy is administered every 3-4 weeks.

  • Reasons for Procedure


    It is used to treat disorders of the immune system, such as:

    • Autoimmune disease—the body begins to attack its own cells
    • Immunodeficiency—low-functioning immune system
    • Inflammatory diseases
    • Other diseases that weaken the immune system

    IVIg can also reduce inflammation in the body. Some conditions, including acute infections, may need IVIg to restore antibodies and boost the immune system.

  • Possible Complications


    Complications are rare, but no procedure is completely free of risk. If you are planning to have IVIg, your doctor will review a list of possible complications, which may include:

    • Headache
    • Infection
    • Fluid in the lungs
    • Damage to the kidneys
    • Blood clots
    • Allergic reaction to the IVIg