Treatment of severely calcified coronary arteries

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts (ECLIPSE)

January 17, 2018

  • Clinical Trial Information

    Trial Contact: Noel, Henry

    Trial Phone: 321.841.3686

  • IRB No: 17.009.02

    Protocol Abbrev: ECLIPSE

    Principal Investigator: Mark A. Steiner, MD

    Sub Investigators: Dalton, Robert MD; Kasi, Vijaykumar MD; Garcia Fernandez, Joel A MD; Khawaja, Farhan MD; Gupta, Ashish MD

    Phase: Device: Significant Risk

    Age Group: Adult

    Secondary Protocol No: CLN-0011-P

    Treatment: Procedural

    Applicable Disease Sites: Coronary Artery Disease

    Therapies Involved: OCT vs Ballon angioplasty

    ClinicalTrials.gov ID: NCT03108456

  • Objective

    To evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique
    for the treatment of severely calcified lesions prior to implantation of drug-eluting stents
    (DES).

  • Key Eligibility

    The target lesion is a new(non-restenotic) coronary lesion.