About Clinical Trials
A clinical trial is a type of research that helps medical professionals leam about benefits and risks associated with promising new treatments or techniques. The ultimate goal of clinical trials is to improve the lives of patients and clinical trials may introduce therapies or technologies before they are available anywhere else.
Types of Clinical Trials
Obesity Trials
Name: Flows
Device: Magnetic anastomosis in bariatric robotic surgery
Disease: Obesity
Status: Enrolment was recently completed with the best performance among the seven sites on the trial. A new study will open next year
Name: REMANN1
Device: Duodenal mucosal resurfacing with thermal energy by endoscopy
Disease: Obesity. Patients who have lost at least 15% total body weight on GLP-1 drug therapy and wish to discontinue their GLP-1 drug without weight regain
Trial website: Remain 1 Study - Fractyl Health Unlock your journey to long-term weight loss
Status: Currently enrolling
Diabetes Trials
Name: RECET
Device: Duodenal mucosal resurfacing regeneration) with electrical pulse by endoscopy Disease: Poorly controlled type 2 diabetes in use of oral medicine and/or GLPI analogue
Trial website: ReCET Study | Type 2 Diabetes | Clinical Trial (patients can self-screen to see if they quality)
Status: Currently enrolling
Name: STEP-1
Device: An intestinal duodenum sleeve will be implanted for nine months by endoscopy, then removed
Disease: Poorly controlled type 2 diabetes using oral meds or injectables
Trial website: StudyType2Diabetes.com/STEP-1 Study
Status: Currently enrolling
New treatments follow strict guidelines and must be approved by the US Food and Drug Administration (FDA) before they are made available for standard use. Clinical trials are a key part of that process.
Manoel Galvao Neto, MD
Director of Research, Orlando Health Weight Loss and Bariatric Surgery Institute
Dr. Manoel Galvao Neto specializes in bariatric and metabolic endoscopy with the Orlando Health Weight Loss and Bariatric Surgery Institute. Widely recognized as one of the most skilled surgical endoscopists in the world, he has been at the forefront of research and innovation in bariatric techniques and procedures since the 1990s. Dr. Galvao Neto has served as a course director and faculty member in bariatric endoscopy programs for renowned medical and surgical societies, including the International Federation for the Surgery of Obesity (IFSO), American Society for Metabolic and Bariatric Surgery (ASMBS), American Society for Gastrointestinal Endoscopy (ASGE), and Association of Bariatric Endoscopy (ABE). He has been awarded the Surgical Innovator Award by the American Society for Metabolic and Bariatric Surgery. While he does not see patients directly, Dr. Galvao Neto’s pioneering work continues to shape the future of bariatric care around the world.
