Journals and Research

Research and education are foundational to the mission of Orlando Health. As frequent contributors to leading publications, our physicians share their research and clinical insights with a national and international community of colleagues.

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Author(s) Title Description Publish Date
Samiksha Gupta, Miloni Parmar, Cody Cox, Chirin Orabi, Heyyan Khalil, Salim Daouk, Brent R Brown Interlobular Septal Thickening in a Young Man With Dyspnea A 30-year-old man with a history of childhood asthma, a 15-pack-year smoking history, and methamphetamine abuse was intubated and started on mechanical ventilation because of acute hypoxic respiratory failure after experiencing progressive dyspnea and a nonproductive cough over the previous year. Du... 12/7/2021
Jenna M Gibilaro, Claire Keating, Luke Benvenuto, Amanda Kramer, Ann Privorotskiy, Yuan Zheng, Cheng-Shiun Leu, Emily DiMango Survival in cystic fibrosis after acute respiratory failure supported by extracorporeal membrane oxygenation andor invasive mechanical ventilation CONCLUSION: Survival for CF patients with acute respiratory failure requiring MV with or without ECMO has improved over time. ECMO may be an appropriate modality for respiratory support in patients with CF and acute respiratory failure who have greater risk of death from MV alone. 9/4/2021
Sarah Weber, Aaron Magh, Michael Hogardt, Volkhard A J Kempf, Maria J G T Vehreschild, Hubert Serve, Sebastian Scheich, Björn Steffen Profiling of bacterial bloodstream infections in hematological and oncological patients based on a comparative survival analysis Bloodstream infections (BSI) are a frequent complication in patients with hematological and oncological diseases. However, the impact of different bacterial species causing BSI and of multiple BSI remains incompletely understood. We performed a retrospective study profiling 637 bacterial BSI episode... 5/4/2021
Sarah Weber, Sebastian Scheich, Aaron Magh, Sebastian Wolf, Julius C Enßle, Uta Brunnberg, Claudia Reinheimer, Thomas A Wichelhaus, Volkhard A J Kempf, Johanna Kessel, Maria J G T Vehreschild, Hubert Serve, Gesine Bug, Björn Steffen, Michael Hogardt Impact of Clostridioides difficile infection on the outcome of patients receiving a hematopoietic stem cell transplantation CONCLUSIONS: CDI was not associated with worse survival in patients receiving a hematopoietic stem cell transplantation, and there were even fewer relapse-related deaths in the AML allo-HSCT cohort. 8/18/2020
Arineh Melkonian, Reenal Patel, Albert Magh, Sampson Ferm, Calvin Hwang Assessment of a Hospital-Wide CIWA-Ar Protocol for Management of Alcohol Withdrawal Syndrome CONCLUSION: Implementation of a Clinical Institute Withdrawal Assessment for Alcohol, Revised-based alcohol withdrawal protocol may significantly improve quality of care, patient safety, and treatment effectiveness in a large, mixed medical/surgical, urban community-based academic medical center. 9/6/2019
Patricia Guzman Rojas, Chirin Orabi, Glenn Speth A Barium Swallow Study Leading to an Incidental Finding on a Screening Colonoscopy Barolith is a mixture of firm feces with barium sulfate, and a frequent cause of obstruction of the appendiceal lumen that can result in appendicitis. Nonetheless, some other complications like aspiration, allergic reaction, and bowel obstruction have also been reported. We present the case of a 71-... 2/20/2018
Pichapong Tunsupon, Ayesha Arshad, Sumit Patel, M Jeffery Mador Incidental Finding of Bronchopulmonary Sequestration in a 64-Year-Old Female CONCLUSION: Pulmonary sequestration can present with recurrent pneumonia in late adulthood. Physicians must review any previous imaging studies of the chest to identify the structural abnormality and be cognizant of differential diagnoses such as infected cystic bronchiectasis, bronchogenic cyst, co... 10/14/2017
Pichapong Tunsupon, M Jeffery Mador The Influence of Body Composition on Pulmonary Rehabilitation Outcomes in Chronic Obstructive Pulmonary Disease Patients CONCLUSION: A comprehensive PR program in COPD patients improved exercise tolerance and quality of life independent of muscle mass depletion or obesity. Similarly, muscle depletion or obesity had no effect on the percentage of patients achieving the MCID for measures of quality of life and exercise ... 10/11/2017
Asma Iftikhar, Albert Magh, Muhammed Azaz Cheema, Sarah Thappa, Sonu Sahni, Stephen Karbowitz Primary pulmonary MALT lymphoma presenting as non-resolving pneumonia Primary lung lymphoma (PLL) is a rare unilateral or bilateral lung disorder that is challenging to diagnose solely based on clinical and radiological presentation. PLL may be misdiagnosed as pneumonia or a lung tumor due to non-specific findings. PLL is most frequently a mucosa-associated lymphoid t... 9/6/2017
Pichapong Tunsupon, Ashima Lal, Mohammed Abo Khamis, M Jeffery Mador Comorbidities in Patients With Chronic Obstructive Pulmonary Disease and Pulmonary Rehabilitation Outcomes CONCLUSION: Patients with cardiac disease experienced greater improvement in the dyspnea score compared with patients with no cardiac disease, whereas patients with orthopedic problems had a smaller but also clinically significant improvement in dyspnea after pulmonary rehabilitation. 4/15/2017
Abdul Hamid Alraiyes, Pichapong Tunsupon, Fayez Kheir, Daniel A Salerno Mediastinal mass diagnosed by endobronchial ultrasound as recurrent hepatocellular carcinoma in a post-liver transplantation patient CONCLUSION: Pulmonologist should be cognizant of diagnostic utility of EBUS-TBNA in this clinical setting as more transplant patients on immunosuppressive medications with enlarged mediastinal lymphadenopathy of unknown origin will be referred for further evaluation. 8/5/2016
Amanda Kovacich, Pranita D Tamma, Sonali Advani, Victor O Popoola, Elizabeth Colantuoni, Leslie Gosey, Aaron M Milstone Peripherally Inserted Central Venous Catheter Complications in Children Receiving Outpatient Parenteral Antibiotic Therapy OPAT OBJECTIVE To identify the frequency of and risk factors associated with complications necessitating removal of the peripherally inserted central catheters (PICCs) in patients receiving outpatient parenteral antibiotic therapy (OPAT) and to determine the appropriateness of OPAT in children with OPAT-... 3/11/2016
Andrei Brateanu, Krishna Patel, Kevin Chagin, Pichapong Tunsupon, Pojchawan Yampikulsakul, Gautam V Shah, Sintawat Wangsiricharoen, Linda Amah, Joshua Allen, Aryeh Shapiro, Neha Gupta, Lillie Morgan, Rahul Kumar, Craig Nielsen, Michael B Rothberg Probability of developing proximal deep-vein thrombosis andor pulmonary embolism after distal deep-vein thrombosis Isolated distal deep-vein thrombosis (DDVT) of the lower extremities can be associated with subsequent proximal deep-vein thrombosis (PDVT) and/or acute pulmonary embolism (PE). We aimed to develop a model predicting the probability of developing PDVT and/or PE within three months after an isolated ... 12/15/2015
Elif Kupeli, Danai Khemasuwan, Pichapong Tunsupon, Atul C Mehta Pills and the air passages a continuum Recently, we reported a number of key, common medications that affect the air passages in a variety of fashions. The purpose of this article is to provide a comprehensive review of the literature on the subject, including supportive articles published in languages other than English. The presented i... 1/7/2015
Danai Khemasuwan, Teerapat Yingchoncharoen, Pichapong Tunsupon, Kenya Kusunose, Ajit Moghekar, Allan Klein, Adriano R Tonelli Right ventricular echocardiographic parameters are associated with mortality after acute pulmonary embolism CONCLUSIONS: Four simple parameters that measure different aspects of the right ventricle (ratio of RV to left ventricular end-diastolic diameter, RV systolic pressure, tricuspid annular plane systolic excursion, and inferior vena cava collapsibility) were independently associated with mortality in ... 1/7/2015
Thomas J J Gintjee, Alvin S H Magh, Carmen Bertoni High throughput screening in duchenne muscular dystrophy from drug discovery to functional genomics Centers for the screening of biologically active compounds and genomic libraries are becoming common in the academic setting and have enabled researchers devoted to developing strategies for the treatment of diseases or interested in studying a biological phenomenon to have unprecedented access to l... 11/19/2014
Pichapong Tunsupon, Tanmay S Panchabhai, Danai Khemasuwan, Atul C Mehta Black bronchoscopy A presence of black pigmentation involving the endobronchial tree is not uncommon. It was first described in the literature in association with occupational exposure in the early 1940s. However, in 2003, Packham and Yeow formally used the term black bronchoscopy to describe endobronchial metastasis ... 11/6/2013