The Orlando Health Arnold Palmer Hospital for Children Division of Genetics treats children and adults with rare genetic conditions including metabolic disorders. Established in 1992, it is the most comprehensive pediatric medical genetics center in Central Florida. Our multidisciplinary team includes board-certified pediatric geneticists, an advanced registered nurse practitioner, board-certified genetic counselors, a registered dietitian, a certified pediatric nurse and other staff members dedicated to providing personalize and compassionate care to patients and their families.

Treating genetic conditions related to:

• Arteriovenous Malformations
• Autism
• Cancer Syndromes
• Cardiac Disorders
• Chromosomal Anomalies
• Congenital Anomalies
• Connective Tissue Disorders
• Dermatological Disorders
• Enzyme replacement therapy
• Eye Disorders
• Hearing Loss
• Hematological Disorders
• Immunodeficiencies
• Intellectual Disability
• Kidney disorders
• Metabolic Disorders
• Mitochondrial Disorders
• Neurodegenerative Disorders
• Neuromuscular conditions
• Orthopedic Disorders

Contact: (407) 648-7802

The Bleeding and Clotting Disorders Program, part of the Haley Center for Children’s Cancer and Blood Disorders at Orlando Health Arnold Palmer Hospital for Children, strives to provide comprehensive expert medical care to children with bleeding and clotting disorders. Through education and advocacy, we have created a program that empowers the bleeding and clotting patients to advocate for themselves and their community. Currently the program team has two comprehensive clinics per month. One clinic is dedicated to those with hemophilia or severe bleeding disorders with participation from physical therapy, social work, and hematology provider. The second clinic is the young women with bleeding disorder clinic, with participation from adolescent gynecology and hematology team.

Conditions Treated:

• Deep vein thrombosis
• Heavy menstrual bleeding
• Hemophilia
• Platelet disorders
• Pulmonary embolism
• Rare bleeding disorders
• Rare clotting deficiencies
• Stroke
• Von Willebrand disease

Contact: (321) 841-7744

Patients with suspected, uncommon, severe, or persistent infections are evaluated and treated at the Orlando Health Arnold Palmer Hospital for Children Infectious Diseases and Immunology practice.  Many infections caused by bacteria, viruses, fungi or parasites can be challenging for a general pediatrician to treat because of the infection’s severity, location or its unusual presentation. A pediatric infectious diseases specialist is a licensed pediatrician with expertise in the evaluation and management of these infections in newborns, children and adolescents. Many patients with undiagnosed immunodeficiencies can have unusual presentations delaying diagnosis for years and our healthcare team works with our patients to diagnosis and treat complex infections.

Conditions treated:

• Bone and joint infections
• Chronic and recurrent infections
• Chronic wounds
• Clostridium difficile infections
• Congenital infections
• COVID-19 in children
• Fevers or illnesses of unclear cause; prolonged or recurrent
• Immunodeficiency syndromes
• Immunoglobulin replacement
• Infections associated with surgery or prosthetic devices
• Kawasaki disease
• Multisystem inflammatory syndrome in children
• MRSA infections (recurrent or refractory to therapy)
• Outpatient parenteral therapy
• Skin infections
• Travel medicine

Contact: (321) 841-7360

The Orlando Health Comprehensive ALS Center, part of the Orlando Health Neuroscience Institute, is the only comprehensive center of its kind in Central Florida dedicated to the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. It is a multidisciplinary center consisting of physical therapy, occupational therapy, speech therapy, physicians, nurses, registered dietitians, respiratory therapy and social workers. The multidisciplinary team works together with patients to acknowledge all for their needs in one visit.

Conditions Treated:

• Amyotrophic lateral sclerosis

Contact: (321) 842-9805

The Orlando Health Muscular Dystrophy Clinic, part of the Orlando Health Neuroscience Institute, is a multidisciplinary and supportive clinic consisting of physical therapy, occupational therapy, speech therapy, physicians, nurses, registered dietitians, respiratory therapy and social workers. Patients with every hereditary disorder partner with their healthcare team throughout their treatment and for their support needs. The team also works with the patient to ensure connectivity to additional healthcare specialists as needed including cardiology, pulmonology and orthopedics.

Conditions treated:

• All hereditary disorders

Contact: (321) 842-9805

Orlando Health Medical Group Infectious Disease provides comprehensive services for the diagnosis and treatment of conditions caused by microbes (bacteria, fungi, viruses and protozoans) and larger agents of disease. Our physicians are recognized experts, specializing in providing diagnoses and treatment of complex conditions such as hepatitis, pneumonia, meningitis and AIDS. Services are provided on both an inpatient and outpatient basis, through collaborative physician consultation, allowing our patients to receive the highest quality of care.

Conditions treated:

• HIV
• AIDS
• Hepatitis B and C
• Mycobacterial infections (tuberculosis, mycobacterium avium complex [MAC], rapidly-growing mycobacteria)
• Fungal infections (aspergillosis, histoplasmosis, blastomycosis, coccidioidomycosis, sporotrichosis, recurrent candidiasis)
• Nocardiosis, actinomycosis
• Parasitic infections (malaria)
• Viral infections (cytomegalovirus [CMV], Epstein-Barr virus [EBV], West Nile virus, enterovirus)
• Pneumonia
• Acute and chronic osteomyelitis, prosthetic joint infections, septic arthritis
• Skin and soft tissue infections (cellulitis, myositis)
• Diabetic foot infections
• Infections of the central nervous system (meningitis, encephalitis, brain abscess)
• Infections with multidrug-resistant organisms (MRSA, VRE, ESBL, Kpc)
• C. difficile infection and other causes of infectious diarrhea
• Refractory H. pylori infection
• Genitourinary infections (recurrent UTI, prostatitis, urethritis, vaginitis)
• Endovascular infections (bacteremia, endocarditis)
• Immunodeficiencies (immunoglobulin deficiencies, leukopenia, chemotactic defects)
• Bloodstream infections (bacteremia)
• Bone and joint infections
• Infectious complications of chemotherapy
• Infections in transplant recipients
• Fever of unknown origin
• Postsurgical infections
• Sepsis
• Sexually transmitted diseases
• Port infections
• Lyme disease 

Contact: (407) 423-1039

The Orlando Health Advanced Rehabilitation Institute Outpatient Center works with individuals with rare neurological diagnoses in a multidisciplinary team setting, including physical therapy, occupational therapy, and speech therapy. We have an assistive technology clinic which includes complex wheelchair seating and positioning and augmentative and alternative communication device specialty evaluations. Our team also provides therapy focusing on wheelchair seating and positioning as it relates to the pediatric transition into adulthood.

Conditions Treated:

• Amyotrophic lateral sclerosis (ALS)
• Glioblastoma
• Guillain barre
• Multiple sclerosis (MS)
• Muscular dystrophy
• Spina bifida
• Spinal muscular atrophy (SMA)
• Transverse myelitis

Contact: (321) 841-3220

The Orlando Health Scripts Specialty Pharmacy strives to improve outcomes for patients with chronic, often complex, or rare conditions. Our pharmacy services aim to reduce barriers to staying on therapy, and include personalized patient education, side effect management, adherence monitoring, and assistance in obtaining copay assistance and locating patient support resources.

Conditions Treated:

• Cystic fibrosis
• Hereditary transthyretin amyloidosis (ATTF)
• Idiopathic pulmonary fibrosis (IPF)

Contact: (321) 842-1622

The Orlando Health Center for Innovation foundry project is focused on pediatric to adult care transitioning (also known as PACT). PACT has focused on helping our pediatric patients, and their families and caretakers. with certain conditions navigate and transition smoothly into adulthood by providing content and booklets that have been created by subject matter experts. We have completed booklets that focus on general adult skills, spina bifida, sickle cell, hemophilia and currently working on Von Willebrand’s disease. Each booklet has content on their condition in detail, causes of and types, how to manage it, symptoms, medications, nutrition, physical activities they can do, urology, mental health, monitoring, treatment centers, how to make safe choices, insurance and more.  The booklets go into great details of how the patient can start taking ownership of their health and feel comfortable doing so.

Conditions of focus:

• Hemophilia
• Sickle Cell
• Spina bifida
• Von Willebrand's disease

Contact: (321) 843-7016

The Orlando Health Cancer Institute (OHIC) providers multidisciplinary cancer care throughout the Central Florida region. They offer both inpatient and outpatient services including diagnosis, surgical oncology, medical oncology/chemotherapy, radiation oncology/therapy, genetics and high-risk clinic, lung cancer screening clinic, survivorship clinics, oncology-specific nutrition, rehabilitation, social work and palliative and hospice services. OHIC also offer patient navigation and integrative medicine through the Cancer Support Community.

Conditions treated:

• Acute erythroid leukemia
• Acute lymphoblastic leukemia
• Acute megakaryoblastic leukemia
• Acute myeloid leukemia
• Acute promyelocytic leukemia
• Adenocarcinoma of appendix
• Adenosarcoma of uterus
• Adenosquamous carcinoma of endometrium
• Adrenal cancer
• Adult t-cell leukemia/lymphoma
• Anal cancer
• Anaplastic astrocytoma
• All malignant cancer types, benign and malignant hematology

Contact: (321) 841-1869

Orlando Health Arnold Palmer Hospital for Children Center for Digestive Health and Nutrition Provides care for both pediatric and young adult patients with appropriate diagnosis and therapeutic care for various types of common and rare disorders. Orlando Health Arnold Palmer Hospital Specialty Diagnosis and Translational Research Laboratory conducts research on various kinds of diseases with the application of multidisciplinary scientific experiments using conventional basic science and advanced multiomic approaches including molecular genetics, transcriptomics, proteomics, microbiomics and metabolomics.

We also offer the Orlando Health Arnold Palmer Hospital for Children Feeding Difficulties Center, which supports children and their families through challenges such as food allergies, chewing or swallowing problems, digestion issues or picky children.

Conditions treated:

• Achalasia
• Alpha-1 antitrypsin (AAT) deficiency
• Autoimmune hepatitis
• Behçet's disease with gastrointestinal manifestations
• Biliary atresia
• Celiac disease
• Congenital malformations/metabolic issues in the neonatal period
• Congenital Sucrase Isomaltase Deficiency (CSID)
• Cyclic vomiting syndrome (CVS)
• Cystic Fibrosis - gastrointestinal manifestation
• Eosinophilic gastrointestinal disorders
• Exocrine pancreatic insufficiency
• Hereditary or autoimmune pancreatitis
• Hirschsprung’s disease
• Hirschsprung's disease
• Hypophosphatasia (HPP)
• Intestinal pseudo-obstruction
• Isolated alpha glucoamylase deficiency
• Isolated lipase deficiency
• Isolated maltase deficiency
• Lesch-Nyhan syndrome (LNS)
• Levator syndrome
• Liver glycogen storage disorders
• Liver metabolic disorders
• Lysosomal Acid Lipase Deficiency (LALD)
• Mastocytic enterocolitis
• Mitochondrial disorders/Mitochondrial cytopathy
• Monogenic inflammatory bowel disease (IBD)
• Polyposis syndromes
• Rumination disorder
• Short bowel syndrome
• Wilson disease

Contact: (321) 841-3338

The Orlando Health Arnold Palmer Hospital for Children Tuberous Sclerosis Clinic provides a multidisciplinary clinic for patients with tuberous sclerosis. The specialties involved are- neurology, genetics, neuro-oncology, nephrology, cardiology, gastroenterology, dermatology and neurosurgery. The clinic accepts pediatric patients and provides care into adulthood and beyond.

Conditions treated:

• Tuberous sclerosis

Contact: (321) 842-6671

The Orlando Health Arnold Palmer Hospital for Children Cystic Fibrosis Center provides a multidisciplinary clinic for patients with cystic fibrosis. We include pediatric pulmonology, pediatric gastroenterology, genetics, pediatric clinical psychology and pediatric endocrinology. Our core team is made up of five pulmonologists, two pediatric nurse practitioners, a dedicated cystic fibrosis nurse, dietician, social worker and a patient navigator (medical assistant).

Conditions treated:

• Cystic fibrosis

Contact: (321) 841-6350

The Orlando Health Arnold Palmer Hospital for Children treats patients ages zero to 21. It is multidisciplinary program with several pediatric specialties including gastroenterology, urology, neurosurgery, orthopedics, rehabilitation, physical medicine and rehabilitation, social work, pulmonary and sleep medicine and fetal care. Patients are seen by all specialties individually during the same visit. Providers then meet immediately after the clinic to discuss each patient as a group.

Conditions treated:

• Spina bifida

Contact: (321) 841-5683

The Orlando Health Heart and Vascular Institute provides a multidisciplinary approach to diagnosis and management of patients with amyloidosis.  They work closely with specialists from various Orlando Health institutes to include hematology and oncology, cardiology, orthopedics, nuclear medicine, genetics and neurology. Orlando Health currently has a grant for an amyloid nurse navigator, who assists with scheduling and testing to get a timelier diagnosis and treatment for patients.

The Orlando Health Heart and Vascular Institute has several programs and clinics dedicated to rare diseases including an amyloidosis clinic, heart failure program, congenital heart failure program and electrophysiology and arrythmia center.

The Orlando Health Multiple Sclerosis Comprehensive Care Center providers the highest level of care for multiple sclerosis patients and is a designated Comprehensive Care Center. The center uses a multidisciplinary approach for patients including physicians, nurses, physical therapy, occupational therapy, speech and language therapy and social work.

Conditions treated:

• Multiple sclerosis
• Transverse myelitis
• Neuromyelitis optica

Contact: (321) 841-2800

Orlando Health Arnold Palmer Hospital for Children Craniomaxillofacial Surgery specialty practice has a subspecialized team, providing state-of-the-art care for infants, children and adolescents with a variety of congenital and acquired facial conditions.

We offer prenatal counseling to support families throughout their journey. The multidisciplinary cleft and craniofacial disorders team provides treatment that is comprehensive, compassionate and highly personalized.

Conditions treated:

• Binder syndrome
• Cherubism
• Cleft lip and palate
• Cranial and facial asymmetry
• Craniofacial Fibrous Dysplasia
• Craniosynostosis (abnormal head shape)
• Cysts and tumors of the face and jaws
• Hemangiomas/vascular malformations
• Juvenile rheumatoid-arthritis-related jaw disorders
• Nager syndrome
• Nasal and jaw deformities
• Oculo-auriculo-vertebral spectrum (Goldenhar syndrome, craniofacial microsomia)
• Pierre Robin sequence
• Treacher Collins syndrome
• Other oral and facial asymmetry and facial abnormalities

Contact: (407) 839-8407

The Orlando Health Arnold Palmer Hospital for Children Metabolic Bone Program offers comprehensive care for bone conditions in children. By partnering with the pediatric endocrinology center, children receive the proper nutrients and care to overcome his or her condition.

Conditions treated:

• Albright’s hereditary osteodystrophy
• Brittle bone disease
• Fibrous dysplasia
• Osteoporosis
• Parathyroid disorders
• Rickets

Contact: (321) 841-3303

The Orlando Health Arnold Palmer Hospital for Children Diabetes Program assists children with type 1 or type 2 diabetes.  The team of physicians, diabetes educators and dietitians will work with children and their families to develop a long-term care plan.

Contact: (321) 841-3303

The Howard Phillip Center for Children and Families serves the most at-risk families in Central Florida. We help thousands of toddlers with special needs, children who have been abused and teens who lack access to healthcare with our comprehensive services.

Services include a child protection team, a developmental center, a child’s advocacy center, and a school-based mobile healthcare unit called Teen Xpress.

Contact: (407) 317-7430